The Association between Gravidity and Primary Biliary Cirrhosis

Primary Biliary Cirrhosis and Mitral Stenosis: A Rare Association

Primary biliary cirrhosis is a rare cause of chronic liver disease in Myanmar. It usually presents with pruritus and fatigue in a middle-aged female before the appearance of jaundice. This case illustrates a woman presenting with 15 years of pruritus and 5 years of intermittent jaundice. She had no risk factors for viral hepatitis and was a non-drinker. Multiple consultations were done and trea...

Primary biliary cirrhosis and myopathy: an uncommon association.

Primary biliary cirrhosis (PBC) is a cholestatic liver disease, which is characterized by a chronic inflammatory destruction of intrahepatic bile ducts. It is a rare disorder whose precise etiology is still to be elucidated. Even though the liver is the principal target of PBC, other organ systems also might be affected. Muscular involvement has rarely been described in this disease, and in the...

Asymptomatic primary biliary cirrhosis.

Primary biliary cirrhosis.

Primary biliary cirrhosis is a chronic liver disease characterised by intrahepatic bile-duct destruction, cholestasis, and, in some cases, cirrhosis. Evidence supporting the autoimmune nature of this disorder includes the appearance of highly specific antimitochondrial antibodies (AMAs) and autoreactive T cells. Concordance rates in monozygotic twins, familial prevalence, and genetic associatio...

Primary Biliary Cirrhosis

Primary Biliary Cirrhosis (PBC) is the result of long-standing damage to intra-hepatic biliary channels as a result of immune mechanisms leading to cholestasis and its associated complications. It can end up in chronic liver disease or cirrhosis. It usually manifests as pruritis that then proceeds to fatigue, jaundice and other features of chronic liver disease. It is detected by raised serolog...